Santioni's Authentic Italian Restaurant and cooking in Fleming Island, Orange Park, Jacksonville Florida. Santioni's Italian Restaurant prepares authentic homemade style italian food - old world family recipes from the northern and southern regions of Italy. Featurning Home made garlic bread, pasta, pizza, grilled chops, salads, veal dinners, chicken dinners, seafood dinners, calzones, and kids meals are on their new menu. Soon to come, vegan dinner meals and gluten free pastas. A large selection of fine wines are also available. Located at 3535 Highway 17, Fleming Island, FL 32003. Call ahead (904) 264-1331 for Italian take out orders. Take out can be picked up at our drive thru window.


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Our New Menu
Appetizers, Salads & Soups, Pastas & Specialties, Chicken Dinners, Veal Dinners, Seafood Dinners, Grilled Steaks and Chops, Childrens Menu, Pizza, Calzones, Side Orders, Desserts, Beer and a large assortment of fine wines!  Call us for take-out orders at: (904) 264-1331.  We have a drive-thru pick up window for your convenience!

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Home made garlic bread, pasta, pizza, grilled chops & steaks, salads, veal dinners, chicken dinners, seafood dinners, calzones, and kids meals. Call ahead and pick up at our drive thru pick-up window!
Santioni's Italian Restaurant is located at 3535 Highyway 17, Fleming Island, FL 32003 | (904) 264-1331.

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